ea0090p419 | Pituitary and Neuroendocrinology | ECE2023
Ribeiro de Oliveira Longo Schweizer Junia
, Schilbach Katharina
, Haenelt Michael
, Pauline Gagliardo Anica
, Peters Anette
, Thorand Barbara
, Stormann Sylvere
, Schopohl Jochen
, Bidlingmaier Martin
Background: Alpha klotho is a transmembrane protein that regulates calcium metabolism. Its soluble portion has been linked to endocrine functions. We have recently shown high concentrations of serum soluble alpha klotho (sαKL) in active acromegaly. There is limited information about regulation of sαKL secretion. We aimed to gain insight about sαKL as a potential biomarker for H-related diseases.Methods: SαKL was measured by ELISA (IBL...